Aliphatic and Polyhalogenated Carcinogens: Structural Bases and Biological Mechanisms
Okt 2013 · Academic Press
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Chemical Induction of Cancer: Structural Bases and Biological Mechanisms, Volume IIIB: Aliphatic and Polyhalogenated Carcinogens covers environmentally and occupationally significant carcinogens of industrial origins. The book discusses the structure-activity relationships, metabolism, and environmental significance of the halogenated linear alkanes and alkenes and the halogenated cycloalkanes; and cycloalkene pesticides, biphenyls, and related aromatics. The text also describes the structure-activity relationships, metabolism, and environmental significance of the halogenated phenoxy acids, aromatic ethers, dibenzofurans, and dibenzo-p-dioxins; and ethylene glycol, diethylene glycol, dioxane, and related compounds. The structure-activity relationships, metabolism, and environmental significance of phenols and phenolic compounds; nitroalkanes and nitroalkenes; and acetamide, dimethylcarbamyl chloride, and related compounds thiocarbonyl compounds are also encompassed. The book further tackles the structure-activity relationships, metabolism, and environmental significance if fatty acids, detergents, and other surfactants with oncogenic potential. The text then looks into the effect of chemical reactivity, molecular geometry, and metabolism on carcinogenic activity. Chemists, geneticists, and those involved in cancer research will find the book invaluable.
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