Antiphospholipid Syndrome: Unraveling the Complexities of Pathophysiology, Diagnosis, and Holistic Management

The treatise begins with a thorough examination of the definition and historical background of APS, tracing its recognition and understanding over time. The classification of antiphospholipid antibodies, including anticardiolipin antibodies, lupus anticoagulant, and beta-2 glycoprotein I antibodies, is meticulously detailed in subsequent chapters, providing a foundation for understanding the pathophysiological underpinnings of the syndrome.

Chapters on epidemiology and prevalence offer insights into the varied impact of APS across demographics, setting the stage for a comprehensive discussion on the structure of blood vessels, hemodynamics, and the pivotal role of endothelial cells. The treatise then navigates through the intricate terrain of the immune system, mechanisms of autoimmunity, and the specific types and functions of antiphospholipid antibodies.