Dive into the comprehensive world of Gastrointestinal Stromal Tumor (GIST) management with our treatise. Explore an in-depth examination of GIST epidemiology, risk factors, pathophysiology, and genetic underpinnings. Delve into the intricate structures and functions of the digestive system, cellular components, and signaling pathways implicated in GIST development. Uncover the latest advances in histological features, molecular testing, radiological imaging, and endoscopic evaluation for precise diagnosis and staging. From symptoms and differential diagnosis to surgical and targeted therapeutic interventions, we cover every aspect of GIST care. Learn about survivorship issues, psychological impact, and supportive care services tailored to enhance the holistic well-being of GIST patients. Whether you're a healthcare professional or seeking comprehensive insights, our treatise offers a definitive guide to navigating the complexities of GIST management.