Explore the comprehensive treatise on Dissociative Disorders, delving into their definition, classification, epidemiology, and etiology. Uncover the intricate neurobiology behind dissociation and unravel the symptomatology, diagnostic criteria, and challenges in diagnosis. Discover the profound impact of trauma, attachment theory, and developmental perspectives on dissociative disorders. Dive into the neurobiological and genetic underpinnings, neuroimaging findings, and pharmacological approaches. Unveil the world of psychotherapeutic modalities, holistic approaches, and emerging interventions. Embark on a journey through mindfulness-based interventions, art therapy, and neurofeedback techniques. This treatise also navigates the landscape of early intervention programs and future directions in prevention research, offering invaluable insights and evidence-based strategies for clinicians, researchers, and stakeholders in the field of mental health.