Super Agers: An Evidence-Based Approach to Longevity – The New York Times Bestseller
Jul 2025 · Random House
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About this ebook
'An extraordinary book that offers a reality check as well as a blueprint for the future.'
Siddhartha Mukherjee, author of The Emperor of All Maladies
'A highly readable and engaging tour de force, Eric Topol takes on a field full of overblown or premature claims, using his personal expertise as a physician to wade through the mass of conflicting evidence to separate fact from hype and pseudoscience, and show us a path to healthy aging.'
Venki Ramakrishnan, Nobel Laureate and author of Why We Die
The New York Times Bestseller
A detailed guide to a revolution transforming human longevity -- a breakthrough moment in the history of human health care -- from one of the most respected medical researchers in the world.
In this breakthrough moment in the history of human health care, Super Agers is an evidenced-based guide to the revolution transforming human longevity. From his unique position as a leader overseeing millions in research funding, Dr Topol explains how you can benefit from new the treatments becoming available at a faster rate than ever, and the fundamental reasons — from semaglutides to AI — that we can be confident these breakthroughs will continue.
More than a quarter of the adult population lives with two or more chronic diseases, with that figure increasing to over half in individuals aged 65 and older. Dr Topol explains the power of the new approaches to the worst chronic killers — diabetes/obesity, heart disease, cancer, and neurodegeneration—and how treatments can begin long before middle age, and even long after. In thirty years, we will have five times as many people at least one hundred years old and they will be healthier than ever because of the breakthroughs Super Agers describes.
These remarkable discoveries are deeply inspiring about our human potential. We can now realistically see how we can make considerable headway for preventing age-related diseases and may one day be able to slow the body-wide aging process itself.
'Imagine a world where diseases once thought incurable are treated, where we are healthier for longer. This future is getting close thanks to a radical convergence of AI and bioscience. In this gripping, vitally important and meticulously researched account, Eric Topol reveals the extraordinary breakthroughs that are transforming medicine—and our lives.'
Mustafa Suleyman, author of The Coming Wave
Siddhartha Mukherjee, author of The Emperor of All Maladies
'A highly readable and engaging tour de force, Eric Topol takes on a field full of overblown or premature claims, using his personal expertise as a physician to wade through the mass of conflicting evidence to separate fact from hype and pseudoscience, and show us a path to healthy aging.'
Venki Ramakrishnan, Nobel Laureate and author of Why We Die
The New York Times Bestseller
A detailed guide to a revolution transforming human longevity -- a breakthrough moment in the history of human health care -- from one of the most respected medical researchers in the world.
In this breakthrough moment in the history of human health care, Super Agers is an evidenced-based guide to the revolution transforming human longevity. From his unique position as a leader overseeing millions in research funding, Dr Topol explains how you can benefit from new the treatments becoming available at a faster rate than ever, and the fundamental reasons — from semaglutides to AI — that we can be confident these breakthroughs will continue.
More than a quarter of the adult population lives with two or more chronic diseases, with that figure increasing to over half in individuals aged 65 and older. Dr Topol explains the power of the new approaches to the worst chronic killers — diabetes/obesity, heart disease, cancer, and neurodegeneration—and how treatments can begin long before middle age, and even long after. In thirty years, we will have five times as many people at least one hundred years old and they will be healthier than ever because of the breakthroughs Super Agers describes.
These remarkable discoveries are deeply inspiring about our human potential. We can now realistically see how we can make considerable headway for preventing age-related diseases and may one day be able to slow the body-wide aging process itself.
'Imagine a world where diseases once thought incurable are treated, where we are healthier for longer. This future is getting close thanks to a radical convergence of AI and bioscience. In this gripping, vitally important and meticulously researched account, Eric Topol reveals the extraordinary breakthroughs that are transforming medicine—and our lives.'
Mustafa Suleyman, author of The Coming Wave
Ratings and reviews
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PatEpicans
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August 17, 2025
excellent
About the author
Dr. Eric Topol is the executive vice president and a professor of molecular medicine at Scripps Research, the largest non-profit biomedical institute in the United States. He is also founder and director of the Scripps Research Translational Institute and a practicing cardiologist. He is one of the top ten most cited researchers in medicine, known for his ground-breaking studies on AI in medicine, genomics, and digitized clinical trials. He was named to the Time 100 Health list of the most influential people in health in 2024. Dr. Topol writes the Substack newsletter Ground Truths and is the author of The Creative Destruction of Medicine, The Patient Will See You Now and Deep Medicine.
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