Osteoimmunology: Interactions of the Immune and Skeletal Systems, Edition 2

· · · ·
· Academic Press
5.0
1 review
Ebook
376
Pages
Eligible
Ratings and reviews aren’t verified  Learn More

About this ebook

Osteoimmunology: Interactions of the Immune and Skeletal Systems, Second Edition, explores the advancements that have been made in the field during the last 40 years, including valuable information on our understanding of the interactions between hematopoietic, immune, and bone cells, now known as the field of osteoimmunology. This comprehensive work offers the most extensive summaries of research trends in the field and their translation into new therapeutics. Early chapters deal with the development of osteoblasts, osteoclasts, hematopoietic stem cells, T and B-lymphocytes, and communications between these cellular elements, while later sections contain discussions of the signaling pathways by which RANKL influences osteoclast development and function. Subsequent chapters explore the effects that estrogen has on bone and the immune system, the development of pathologic conditions, and the growing research around osteoporosis, Paget's disease, the genetics of bone disease, and bone cancer metastasis. - Explains the intricate interaction between the immune system and bone - Features detailed discussions of the key cellular and molecular mechanisms governing the homeostasis of the individual systems - Facilitates greater understanding of osteoimmunologic networks, their environments, and how this understanding leads to better treatments for human diseases involving both systems

Ratings and reviews

5.0
1 review

About the author

Dr. Lorenzo is Professor of medicine in the Division of Endocrinology and Metabolism and Director of Bone Biology Research at the University of Connecticut Health Center. He is a nationally renowned expert on bone remodeling and its effect on bone health.

Dr. Horowitz is Professor of Orthopaedics and Rehabilitation at the Yale University School of Medicine. His research interests include the interactions between the skeletal, immune, and hematopoietic systems as they relate to normal and pathologic bone remodeling.

Dr. Choi is Professor of Pathology and Laboratory Medicine, University of Pennsylvania; Investigator, The Leonard and Marilyn Abramson Family Cancer Research Institute, Philadelphia, PA.

Dr. Takayanagi is Professor in the Department of Cell Signaling, Tokyo Medical and Dental University. His group studies the mechanism of bone destruction in rheumatoid arthritis, which focuses on the regulation of osteoclasts by T cells. This interdisciplinary field, osteoimmunology, covers various research on shared mechanisms and interactions between immune and bone systems.

Rate this ebook

Tell us what you think.

Reading information

Smartphones and tablets
Install the Google Play Books app for Android and iPad/iPhone. It syncs automatically with your account and allows you to read online or offline wherever you are.
Laptops and computers
You can listen to audiobooks purchased on Google Play using your computer's web browser.
eReaders and other devices
To read on e-ink devices like Kobo eReaders, you'll need to download a file and transfer it to your device. Follow the detailed Help Center instructions to transfer the files to supported eReaders.