Microbial Resistance Evolution

The book adopts a progressive approach, starting with the basics of microbial genetics and antimicrobial action, before moving into complex evolutionary scenarios. It covers topics like mobile genetic elements, the impact of selective pressures, and specific resistance mechanisms such as enzymatic degradation. The overuse of antibiotics has fueled the selection and proliferation of resistant strains, highlighting the need for antimicrobial stewardship.

The book emphasizes the importance of evolutionary principles in predicting and managing resistance, offering insights valuable to students, researchers, and healthcare professionals alike. The concluding chapters provide a comprehensive overview of antimicrobial resistance and propose strategies for combating it, including novel therapeutics and improved infection control practices. This interdisciplinary approach integrates evolutionary biology, pharmacology, and public health to fully understand the complexities of antimicrobial resistance.