Modern Adaptive Randomized Clinical Trials: Statistical and Practical Aspects

· Chapman & Hall/CRC Biostatistics Series Book 81 · CRC Press
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533
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Is adaptive randomization always better than traditional fixed-schedule randomization? Which procedures should be used and under which circumstances? What special considerations are required for adaptive randomized trials? What kind of statistical inference should be used to achieve valid and unbiased treatment comparisons following adaptive random

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