Organic Chemistry: An Acid—Base Approach

· CRC Press
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Based on the premise that many, if not most, reactions in organic chemistry can be explained by variations of fundamental acid-base concepts, Organic Chemistry: An Acid–Base Approach provides a framework for understanding the subject that goes beyond mere memorization. The individual steps in many important mechanisms rely on acid–base reactions, and the ability to see these relationships makes understanding organic chemistry easier. Using several techniques to develop a relational understanding, this textbook helps students fully grasp the essential concepts at the root of organic chemistry.

Providing a practical learning experience with numerous opportunities for self-testing, the book contains:

  • Checklists of what students need to know before they begin to study a topic
  • Checklists of concepts to be fully understood before moving to the next subject area
  • Homework problems directly tied to each concept at the end of each chapter
  • Embedded problems with answers throughout the material
  • Experimental details and mechanisms for key reactions

The reactions and mechanisms contained in the book describe the most fundamental concepts that are used in industry, biological chemistry and biochemistry, molecular biology, and pharmacy. The concepts presented constitute the fundamental basis of life processes, making them critical to the study of medicine. Reflecting this emphasis, most chapters end with a brief section that describes biological applications for each concept. This text provides students with the skills to proceed to the next level of study, offering a fundamental understanding of acids and bases applied to organic transformations and organic molecules.

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Michael B. Smith is a professor of chemistry in the Department of Chemistry at the University of Connecticut, at Storrs. His research interests focus on the identification of bioactive lipids from the dental pathogen Porphyromonas gingivalis, exploration of the use of conducting polymers as a neutral reaction medium for chemical transformations, development of fluorescent probes for the detection of cancerous tumors, and the synthesis of phenanthridone alkaloids. He is also the author of volumes 6–12 of the Compendium of Organic Synthetic Methods and coauthor of the fifth and sixth editions and upcoming seventh edition of March’s Advanced Organic Chemistry. He is the author of the first, second, and upcoming third edition of Organic Synthesis, as well as several monographs. Dr. Smith received his PhD in organic chemistry from Purdue University in 1977.

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