Neurobiology of Aging: Exploring Cognitive Decline and Neurodegeneration

Sachchida Nand Rai

Dec 2025 · Academic Press

Ebook

300

Pages

Eligible

This book will become available on December 1, 2025. You will not be charged until it is released.

About this ebook

Neurobiology of Aging: Exploring Cognitive Decline and Neurodegeneration is a comprehensive reference exploring the complexities of the aging brain. This book examines the intricate processes driving cognitive decline and neurodegeneration. From the gradual loss of neurons and synapses to the formation of protein aggregates characteristic of Alzheimer's disease, each chapter reviews key aspects of brain aging. Chapters dissect the mechanisms driving neuronal loss, synaptic dysfunction, and protein misfolding, shedding light on the intricate interplay of oxidative stress, inflammation, and mitochondrial dysfunction. This book also navigates through strategies for healthy brain aging, from the impact of diet and exercise to the role of cognitive stimulation. - Reviews the complex interplay of various molecular, cellular, and systemic processes that contribute to cognitive decline and neurodegeneration - Discusses genetic influences on aging and neurodegenerative diseases - Outlines various therapeutic approaches to age-related cognitive decline and neurodegenerative diseases

About the author

Dr. Sachchida Nand Rai is a Research Associate (ICMR-RA) at Centre of Experimental Medicine and Surgery, Institute of Medical Sciences, Banaras Hindu University (BHU), Varanasi. Dr. Rai also completed his PhD from the Biochemistry Department (Institute of Science) of the same university in 2018. The BHU consistently ranks among the top universities in India in terms of research output and quality in the life sciences. Before joining the BHU as Research Associate, he was post-Doctoral fellow at Centre of Biotechnology, University of Allahabad, Prayagraj, India. Dr Rai has edited over 100 manuscripts, reviewed more than 900 manuscripts for high-impact journals, and has published 3 books. He is a member of the Indian Academy of Neurosciences and serves as editorial board member for multiple journals such as 3-Biotech, Oxidative Medicine and Cellular Longevity.

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