Viral Mutations Impact

The book begins with viral genetics and evolutionary biology, providing context with examples from influenza, HIV, and SARS-CoV-2. It then dissects drug resistance, referencing Tamiflu-resistant influenza and multi-drug resistant HIV, including the molecular basis of vaccine escape. Understanding these processes is vital because viruses can alter their surface proteins to evade antibodies generated by vaccinations.

The book advocates for a forward-thinking approach integrating evolutionary principles into antiviral drug and vaccine development through drug target selection and real-time surveillance. Computational modeling and AI are useful in predicting viral evolution. By combining virology, biology, life sciences, pharmacology, and immunology, the book provides a pragmatic understanding of applying scientific advancements to manage viral diseases.