By taking into greater account non-humans and relationships between humans and non-humans, this approach offers a re-casting of traditional topics in public health and opens new opportunities for examining these. In so doing, the book raises key questions about researching ‘health’; about considering the extent to which it may be productive to think about health as it interests not only human lives; and what happens to our moral and ethical commitments if we no longer put humans first. This book was originally published as a special issue of Critical Public Health.