It argues that the opioid epidemic represents a systemic failure requiring a coordinated, evidence-based response. For example, the book details the high costs associated with treatment and lost productivity, highlighting the crisis's broad economic impact. Beginning with an introduction to the crisis and its key drivers, the book unfolds logically, tackling the epidemic's evolution and offering deep dives into specific aspects. It culminates in a discussion of potential solutions and strategies for mitigating the impact, making it a valuable resource for public health professionals, policymakers, and anyone seeking to understand and address this critical current event.