The book examines the direct impact of regulations, such as prescription drug monitoring programs, on drug safety using case studies and statistical data. It then delves into unintended consequences, like drug shortages and increased costs. By examining the rise of opioid and other drug epidemics, it highlights the need for adaptive policies that balance benefits and risks. The book progresses from introducing key concepts to analyzing the effects of specific regulations and offering recommendations for improving regulatory strategies and promoting safer medication use.