This guide focuses on a specific form of citizen engagement, namely mini-publics, and their potential to be adapted to a variety of contexts. Mini-publics are forums that include a cross-section of the population selected through civic lottery to participate in evidenceinformed deliberation to inform policy and action. The term refers to a diverse set of democratic innovations to engage citizens in policy-making. This guide provides an overview of how to organize mini-publics in the health sector. It is a practical companion to the 2022 Overview report, Implementing citizen engagement within evidence-informed policy-making. Both documents examine and encourage contributions that citizens can make to advance WHO’s mission to achieve universal health coverage. Anyone interested in, or planning to organize citizen engagement in evidence-informed policy-making can use this guide to find relevant information on how to conduct a minipublic. The guide also offers a structured learning process for organizers, commissioners and facilitators who use the guide to develop an actual citizen engagement project. The structure of the guide allows for flexibility and context-specific circumstances that affect the organizing of a mini-public.