This document, jointly published by the World Health Organization (WHO) and the United Nations Children's Fund (UNICEF), outlines a comprehensive framework for integrating COVID-19 vaccination into existing immunization programs and primary health care systems globally. The report addresses the challenges faced by health systems during the rapid rollout of COVID-19 vaccines and emphasizes the importance of sustainable vaccination strategies beyond the immediate pandemic response. It provides guidance on planning, implementation, and monitoring processes to incorporate COVID-19 vaccination into national immunization programs. The intended audience includes policy makers, public health officials, and healthcare providers involved in immunization and primary healthcare delivery. The document aims to enhance the resilience of health systems and ensure the continued provision of essential health services while adapting to the ongoing pandemic landscape.