HTA is a multidisciplinary process used to evaluate the clinical, economic, ethical implications and social impact of new health technologies. This document describes the critical role of HTA in supporting decision making by informing policy-makers about the adoption and/or reimbursement of medical technologies by healthcare systems. HTA links the three distinct but complementary functions of health technology decision-making, the first being regulatory approval of health technologies for market access, followed by HTA for the adoption of technologies into health systems, and lastly, health technology management across the lifetime of a technology.