WHO Onchocerciasis Technical Advisory Subgroup: report of the eighth meeting, Toledo, Spain, 9-12 December 2024
World Health Organization
Aug 2025 · World Health Organization
Ebook
88
Pages
family_home
Eligible
info
reportRatings and reviews aren’t verified Learn More
About this ebook
The WHO Onchocerciasis Technical Advisory Subgroup (OTS) convened its eighth meeting to review progress and challenges in the global effort to eliminate onchocerciasis. Key topics included alternative treatment strategies, new medicines, monitoring and evaluation (M&E), and addressing complexities in Loa loa co-endemic regions. The group assessed the efficacy of treatments such as moxidectin, ivermectin, and doxycycline under the PICO framework and called for expanded safety evaluations in children and standardized outcome measures. Sustainability concerns prompted calls for new drug supply models beyond donations. The group recommended developing target product profiles (TPPs) for future treatments. The iTAS manual was updated to better integrate onchocerciasis and lymphatic filariasis surveillance. OTS emphasized refining M&E algorithms, enhancing post-treatment and post-elimination surveillance, and incorporating entomological and serological assessments. Data modeling was employed to inform programmatic decisions on stopping mass drug administration (MDA). Concerns were raised about undetected transmission, survey sizes, and diagnostic gaps. OTS endorsed the test-and-not-treat (TaNT) approach using the LoaScope for safe treatment in Loa loa-endemic areas and supported expanded access and operational research. Advances in diagnostics, including new rapid diagnostic tests and PCR methods, were highlighted. The group stressed collaboration between diagnostic and treatment initiatives to drive progress toward elimination.
Rate this ebook
Tell us what you think.
Reading information
Smartphones and tablets
Install the Google Play Books app for Android and iPad/iPhone. It syncs automatically with your account and allows you to read online or offline wherever you are.
Laptops and computers
You can listen to audiobooks purchased on Google Play using your computer's web browser.
eReaders and other devices
To read on e-ink devices like Kobo eReaders, you'll need to download a file and transfer it to your device. Follow the detailed Help Center instructions to transfer the files to supported eReaders.
