Inflammation and Epilepsy: New Vistas
Damir Janigro · Astrid Nehlig · Nicola Marchi
May 2021 · Springer Nature
Ebook
237
Pages
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About this ebook
This book provides comprehensive information, both for clinicians and scientists, on the basic mechanisms, clinical features, and therapeutic approaches to epilepsy as an inflammatory disease. Inflammation has been for many years considered as an etiologic player (and a therapeutic target) for a specific group of epilepsies. However, it turns out that this concept underestimated the impact of inflammation in seizure disorders. Many accepted therapies for non-inflammatory epilepsies act in part as an inflammatory drug. The CNS actively responds to acute immune challenges by altering body temperature, stimulating the HPA axis, as well as up- and down-regulating specific sympathetic pathways.
About the author
Damir Janigro
Department of Physiology and Biophysics
Case Western Reserve UniversityCleveland
Ohio
USA
Astrid Nehlig
INSERM
Strasbourg
France
Nicola Marchi
Cerebrovascular and Glia Research, Department of Neuroscience
Institute of Functional Genomics
Montpellier,
France
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